Article
Development of diabetes in a familial amyotrophic lateral sclerosis patient carrying the I113T SOD1 mutation. Case Report.
Neuro endocrinology letters - 1 Jan 2015
Hamasaki Hidetaka, Takeuchi Yu, Masui Yoshinori, Ohta Yasuyuki, Abe Koji, Yoshino Hiide, Yanai Hidekatsu
Abstract excerpt
Familial amyotrophic lateral sclerosis (ALS) are caused by the mutations in the copper (Cu) / zinc (Zn) superoxide dismutase 1 (SOD1) gene. SOD1 has been reported to play a critical role in glucose metabolism in yeast and cell models, and mice. However, effects of SOD1 for glucose metabolism in humans remain unknown. A 72-year-old woman was admitted to our hospital due to hyperglycemia. She showed severe muscle...
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