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Article

Germline PARP4 mutations in patients with primary thyroid and breast cancers.

Endocrine-related cancer - 1 Mar 2016

Ikeda Yuji, Kiyotani Kazuma, Yew Poh Yin, Kato Taigo, Tamura Kenji, Yap Kai Lee, Nielsen Sarah M, Mester Jessica L, Eng Charis, Nakamura Yusuke, Grogan Raymon H

Abstract excerpt

Germline mutations in the PTEN gene, which cause Cowden syndrome, are known to be one of the genetic factors for primary thyroid and breast cancers; however, PTEN mutations are found in only a small subset of research participants with non-syndrome breast and thyroid cancers. In this study, we ai...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26699384
DOI: 10.1530/ERC-15-0359
PMCID: PMC5152685

Genes

PARP4
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-26699384-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

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Research trail→

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Germline PARP4 mutations in patients with primary thyroid and breast cancers.PMID 26699384Read ↗

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Germline mutations in the breast cancer susceptibility gene PTEN are rare in high-risk non-BRCA1/2 French Canadian breast cancer families.Semantic proximity Read ↗

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Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes.Semantic proximity Read ↗

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