Article
Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Endocrine-related cancer - 1 Mar 2016
Ikeda Yuji, Kiyotani Kazuma, Yew Poh Yin, Kato Taigo, Tamura Kenji, Yap Kai Lee, Nielsen Sarah M, Mester Jessica L, Eng Charis, Nakamura Yusuke, Grogan Raymon H
Abstract excerpt
Germline mutations in the PTEN gene, which cause Cowden syndrome, are known to be one of the genetic factors for primary thyroid and breast cancers; however, PTEN mutations are found in only a small subset of research participants with non-syndrome breast and thyroid cancers. In this study, we aimed to identify germline variants that may be related to genetic risk of primary thyroid and breast cancers. Genomic...
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