Article
Long-term outcome of molecular subgroups of GIST patients treated with standard-dose imatinib in the BFR14 trial of the French Sarcoma Group.
European journal of cancer (Oxford, England : 1990) - 1 Jan 2016
Patrikidou Anna, Domont Julien, Chabaud Sylvie, Ray-Coquard Isabelle, Coindre Jean-Michel, Bui-Nguyen Binh, Adenis Antoine, Rios Maria, Bertucci François, Duffaud Florence, Chevreau Christine, Cupissol Didier, Pérol David, Emile Jean-François, Blay Jean-Yves, Le Cesne Axel
Abstract excerpt
BACKGROUND: The added value of tumoural genomic profiles to conventional clinico-biological factors to predict progression-free survival (PFS) and overall survival (OS) was prospectively investigated in patients with advanced gastrointestinal stromal tumours (GIST) treated in the BFR14 study. METHODS: Of the 434 included patients, mutational analysis was performed in 322 patients. Survival analysis was performed...
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