Article
Support for association between ADHD and two candidate genes: NET1 and DRD1.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2005
Bobb Aaron J, Addington Anjene M, Sidransky Ellen, Gornick Michele C, Lerch Jason P, Greenstein Deanna K, Clasen Liv S, Sharp Wendy S, Inoff-Germain Gale, Wavrant-De Vrièze Fabienne, Arcos-Burgos Mauricio, Straub Richard E, Hardy John A, Castellanos F Xavier, Rapoport Judith L
Abstract excerpt
Attention deficit hyperactivity disorder (ADHD) is a common, multifactorial disorder with significant genetic contribution. Multiple candidate genes have been studied in ADHD, including the norepinephrine transporter (NET1) and dopamine D1 receptor (DRD1). NET1 is implicated in ADHD because of the efficacy of atomoxetine, a selective noradrenergic reuptake inhibitor, in the treatment of ADHD. DRD1 is primarily...
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