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Autophagy postpones apoptotic cell death in PRRSV infection through Bad-Beclin1 interaction

15 Dec 2015

Abstract excerpt

Autophagy and apoptosis play significant roles in PRRSV infection and replication. However, the interaction between these 2 processes in PRRSV replication is still far from been completely understood. In our studies, the exposure of MARC-145 cells to PRRSV confirmed the activation of autophagy and subsequent induction of apoptosis. The inhibition of autophagy by 3-methyladenine (3-MA) caused a significant...

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PMID: 26670824
DOI: 10.1080/21505594.2015.1131381

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