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Article

The Influence of OLR1 and PCSK9 Gene Polymorphisms on Ischemic Stroke: Evidence from a Meta-Analysis.

Scientific reports - 15 Dec 2015

Au Anthony, Griffiths Lyn R, Cheng Kian-Kai, Wee Kooi Cheah, Irene Looi, Keat Wei Loo

Abstract excerpt

Both OLR1 and PCSK9 genes are associated with atherosclerosis, cardiovascular disease and ischemic stroke. The overall prevalence of PCSK9 rs505151 and OLR1 rs11053646 variants in ischemic stroke were 0.005 and 0.116, respectively. However, to date, association between these polymorphisms and ischemic stroke remains inconclusive. Therefore, this first meta-analysis was carried out to clarify the presumed...

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Identifiers

PMID: 26666837
DOI: 10.1038/srep18224
PMCID: PMC4678327

Genes

OLR1
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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