Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes.

doi:10.1161/ATVBAHA.115.306112

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Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2016

Zidar David A, Mudd Joseph C, Juchnowski Steven, Lopes Joao P, Sparks Sara, Park Samantha S, Ishikawa Masakazu, Osborne Robyn, Washam Jeffrey B, Chan Cliburn, Funderburg Nicholas T, Owoyele Adeyinka, Alaiti Mohamad A, Mayuga Myttle, Orringer Carl, Costa Marco A, Simon Daniel I, Tatsuoka Curtis, Califf Robert M, Newby L Kristin, Lederman Michael M, Weinhold Kent J

Abstract excerpt

OBJECTIVE: Inflammation in response to oxidized lipoproteins is thought to play a key role in acute coronary syndromes (ACS), but the pattern of immune activation has not been fully characterized. We sought to perform detailed phenotypic and functional analysis of CD8 T lymphocytes from patients presenting with ACS to determine activation patterns and potential immunologic correlates of ACS. APPROACH AND RESULTS:...

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Identifiers

PMID: 26663396
DOI: 10.1161/ATVBAHA.115.306112
PMCID: PMC5079704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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