Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Construction of CYP1B1 gene haplotypes predisposing to primary congenital glaucoma through allele-specific PCR/restriction fragment length polymorphism analysis].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2015

Zhang Aiping, Li Shengjie, Ouyang Qi, Tang Li, Wang Xiaolei, Ji Jian, Cao Wenjun

Abstract excerpt

OBJECTIVE: To develop an allele-specific PCR (AS-PCR)/restriction fragment length polymorphism (RFLP) assay for CYP1B1 gene haplotypes predisposing to primary congenital glaucoma (PCG). METHODS: Twenty Chinese PCG patients and 20 healthy controls were recruited. Peripheral blood sample was subjected to direct sequencing for common single nucleotide polymorphisms (SNPs) of the CYP1B1 gene. Based on the results,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 CYP1B1
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glaucoma

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Polymorphism, Restriction Fragment Length

Share to Reproducibility of Results

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 26663047
DOI: 10.3760/cma.j.issn.1003-9406.2015.06.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Construction of CYP1B1 gene haplotypes predisposing to primary congenital glaucoma through allele-specific PCR/restriction fragment length polymorphism analysis].PMID 26663047Read ↗

CYP1B1 mutation profile of Iranian primary congenital glaucoma patients and associated haplotypes.Semantic proximity Read ↗

[Analysis of the CYP1B1 gene mutation in primary congenital glaucoma patients of Hubei Han nationality].Semantic proximity Read ↗

Identification of R368H as a predominant CYP1B1 allele causing primary congenital glaucoma in Indian patients.Semantic proximity Read ↗

Glaucoma-associated CYP1B1 mutations share similar haplotype backgrounds in POAG and PACG phenotypes.Semantic proximity Read ↗

Globally, CYP1B1 mutations in primary congenital glaucoma are strongly structured by geographic and haplotype backgrounds.Semantic proximity Read ↗

Primary congenital glaucoma and Rieger's anomaly: extended haplotypes reveal founder effects for eight distinct CYP1B1 mutations.Semantic proximity Read ↗

Investigation of CYP1B1 mutations in Chinese patients with primary congenital glaucoma.Semantic proximity Read ↗

Compound heterozygous mutations in CYP1B1 gene leads to severe primary congenital glaucoma phenotypeSemantic proximity Read ↗

Analysis of CYP1B1 Gene Mutations in Patients with Primary Congenital GlaucomaSemantic proximity Read ↗

Mutation spectrum of CYP1B1 in Chinese patients with primary open-angle glaucoma.Semantic proximity Read ↗

Overview of Cytochrome P450 1B1 gene mutations in patients with primary congenital glaucoma.Semantic proximity Read ↗

Molecular genetics of primary congenital glaucoma in Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.