Article
Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behçet's Disease.
Arthritis & rheumatology (Hoboken, N.J.) - 1 May 2016
Ognenovski Mikhail, Renauer Paul, Gensterblum Elizabeth, Kötter Ina, Xenitidis Theodoros, Henes Jörg C, Casali Bruno, Salvarani Carlo, Direskeneli Haner, Kaufman Kenneth M, Sawalha Amr H
Abstract excerpt
OBJECTIVE: Behçet's disease (BD) is a systemic inflammatory disease with an incompletely understood etiology. Despite the identification of multiple common genetic variants associated with BD, rare genetic variants have been less explored. We undertook this study to investigate the role of rare variants in BD by performing whole exome sequencing in BD patients of European descent. METHODS: Whole exome sequencing...
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