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Artificial oocyte activation with calcium ionophore does not cause a widespread increase in chromosome segregation errors in the second meiotic division of the oocyte.

Fertility and sterility - 1 Mar 2016

Capalbo Antonio, Ottolini Christian S, Griffin Darren K, Ubaldi Filippo Maria, Handyside Alan H, Rienzi Laura

Abstract excerpt

OBJECTIVE: To study the effect of artificial oocyte activation (AOA) on chromosome segregation errors in the meiotic divisions. DESIGN: Prospective cohort study with historical control. SETTING: Private/academic IVF centers. PATIENT(S): Fifty-six metaphase II oocytes were donated from 12 patients who had undergone IVF between June 2008 and May 2009. INTERVENTION(S): Oocytes were activated by 40 minutes' exposure...

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Identifiers

PMID: 26658129
DOI: 10.1016/j.fertnstert.2015.11.017

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