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Article

Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach.

Journal of virology - 15 May 2016

Aljabr Waleed, Touzelet Olivier, Pollakis Georgios, Wu Weining, Munday Diane C, Hughes Margaret, Hertz-Fowler Christiane, Kenny John, Fearns Rachel, Barr John N, Matthews David A, Hiscox Julian A

Abstract excerpt

UNLABELLED: Human respiratory syncytial virus (HRSV) is a major cause of serious respiratory tract infection. Treatment options include administration of ribavirin, a purine analog, although the mechanism of its anti-HRSV activity is unknown. We used transcriptome sequencing (RNA-seq) to investigate the genome mutation frequency and viral mRNA accumulation in HRSV-infected cells that were left untreated or...

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Identifiers

PMID: 26656699
DOI: 10.1128/JVI.02349-15
PMCID: PMC4859727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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