Article

Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation

2019-12-02

Abstract excerpt

<h4>ABSTRACT</h4> The human orthopneumovirus (HRSV) is a major cause of lower respiratory tract infection in children worldwide. Despite decades of efforts, no vaccine is available. In this work, we report mutations that are frequent in vaccine candidates and rare in wild-type genomes, taking into account all the publicly available HRSV sequence data. These mutations are different from the ones already known to a...

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Literature Corpus work: b64fe8b3-2050-52b6-b80f-fbc52b4c870e
DOI: 10.1101/862185

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