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Article

Cautionary tale of using 16S rRNA gene sequence similarity values in identification of human-associated bacterial species.

International journal of systematic and evolutionary microbiology - 1 Jun 2015

Rossi-Tamisier Morgane, Benamar Samia, Raoult Didier, Fournier Pierre-Edouard

Abstract excerpt

Modern bacterial taxonomy is based on a polyphasic approach that combines phenotypic and genotypic characteristics, including 16S rRNA sequence similarity. However, the 95 % (for genus) and 98.7 % (for species) sequence similarity thresholds that are currently recommended to classify bacterial isolates were defined by comparison of a limited number of bacterial species, and may not apply to many genera that...

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PMID: 25736410
DOI: 10.1099/ijs.0.000161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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