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Article

Complex Evolutionary and Genetic Patterns Characterize the Loss of Scleral Ossification in the Blind Cavefish Astyanax mexicanus.

PloS one - 1 Jan 2015

O'Quin Kelly E, Doshi Pooja, Lyon Anastasia, Hoenemeyer Emma, Yoshizawa Masato, Jeffery William R

Abstract excerpt

The sclera is the tough outer covering of the eye that provides structural support and helps maintain intraocular pressure. In some fishes, reptiles, and birds, the sclera is reinforced with an additional ring of hyaline cartilage or bone that forms from scleral ossicles. Currently, the evolutionary and genetic basis of scleral ossification is poorly understood, especially in teleost fishes. We assessed scleral...

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PMID: 26649887
DOI: 10.1371/journal.pone.0142208
PMCID: PMC4674125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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