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Article

Quantitative genetic analysis of retinal degeneration in the blind cavefish Astyanax mexicanus.

PloS one - 1 Jan 2013

O'Quin Kelly E, Yoshizawa Masato, Doshi Pooja, Jeffery William R

Abstract excerpt

The retina is the light-sensitive tissue of the eye that facilitates vision. Mutations within genes affecting eye development and retinal function cause a host of degenerative visual diseases, including retinitis pigmentosa and anophthalmia/microphthalmia. The characin fish Astyanax mexicanus includes both eyed (surface fish) and eyeless (cavefish) morphs that initially develop eyes with normal retina; however,...

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Identifiers

PMID: 23437360
DOI: 10.1371/journal.pone.0057281
PMCID: PMC3577753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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