Melanomas Associated With Blue Nevi or Mimicking Cellular Blue Nevi: Clinical, Pathologic, and Molecular Study of 11 Cases Displaying a High Frequency of GNA11 Mutations, BAP1 Expression Loss, and a Predilection for the Scalp.

doi:10.1097/PAS.0000000000000568

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Article

Melanomas Associated With Blue Nevi or Mimicking Cellular Blue Nevi: Clinical, Pathologic, and Molecular Study of 11 Cases Displaying a High Frequency of GNA11 Mutations, BAP1 Expression Loss, and a Predilection for the Scalp.

The American journal of surgical pathology - 1 Mar 2016

Costa Sebastian, Byrne Michelle, Pissaloux Daniel, Haddad Veronique, Paindavoine Sandrine, Thomas Luc, Aubin Francois, Lesimple Thierry, Grange Florent, Bonniaud Bertille, Mortier Laurent, Mateus Christine, Dreno Brigitte, Balme Brigitte, Vergier Beatrice, de la Fouchardiere Arnaud

Abstract excerpt

Melanomas associated with blue nevi (MABN) or mimicking cellular blue nevi (MMCBN) represent exceptional variants of malignant cutaneous melanocytic tumors. Uveal and leptomeningeal melanomas frequently have somatic mutations of GNAQ or GNA11, which are believed to be early driver mutations. In uveal melanomas, monosomy 3, linked to the BAP1 gene, is an adverse prognostic factor. We have studied the clinical,...

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Identifiers

PMID: 26645730
DOI: 10.1097/PAS.0000000000000568

Genes

BAP1
GNA11
GNAQ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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