Article
Do somatic mutations in de novo MDS predict for response to treatment?
Hematology. American Society of Hematology. Education Program - 1 Jan 2015
Schroeder Mark A, DeZern Amy E
Abstract excerpt
A 68-year-old male with history of hypertension and arthritis presented with bruising and increasing fatigue over several months. He was found to be thrombocytopenic (platelets 30), WCB 2.0 K/mm(3), Hg 11.6 g/dL, ANC 870, and 1% circulating blasts. Bone marrow biopsy revealed 40%-50% cellular with multilineage dysplasia and 10% blasts. Cytogenetic genetic studies showed trisomy 2, and translocation (3;21). FISH...
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