Article
A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain.
EBioMedicine - 1 Oct 2015
Meng Weihua, Deshmukh Harshal A, Donnelly Louise A, Torrance Nicola, Colhoun Helen M, Palmer Colin N A, Smith Blair H
Abstract excerpt
Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK. The purpose of this genome-wide association study (GWAS) was to identify genetic contributors to this disorder. Cases of neuropathic pain were defined as diabetic patients with a multiple prescription history of at least one of...
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