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Cyclin A2: At the crossroads of cell cycle and cell invasion

1 Jan 2015

Abstract excerpt

Cyclin A2 is an essential regulator of the cell division cycle through the activation of kinases that participate to the regulation of S phase as well as the mitotic entry. However, whereas its degradation by the proteasome in mid mitosis was thought to be essential for mitosis to proceed, recent observations show that a small fraction of cyclin A2 persists beyond metaphase and is degraded by autophagy. Its...

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PMID: 26629317
DOI: 10.4331/wjbc.v6.i4.346

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