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Article

High Frequency of Imprinted Methylation Errors in Human Preimplantation Embryos

2 Dec 2015

Abstract excerpt

Assisted reproductive technologies (ARTs) represent the best chance for infertile couples to conceive, although increased risks for morbidities exist, including imprinting disorders. This increased risk could arise from ARTs disrupting genomic imprints during gametogenesis or preimplantation. The few studies examining ART effects on genomic imprinting primarily assessed poor quality human embryos. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26626153
DOI: 10.1038/srep17311

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