Article
Defects in imprinting and genome-wide DNA methylation are not common in the in vitro fertilization population.
Fertility and sterility - 1 Jan 2012
Oliver Verity F, Miles Harriet L, Cutfield Wayne S, Hofman Paul L, Ludgate Jackie L, Morison Ian M
Abstract excerpt
OBJECTIVE: To examine an IVF cohort for imprinted and genome-wide DNA methylation abnormalities. DESIGN: Retrospective study. SETTING: Research laboratory. PATIENT(S): DNA samples from a previously described IVF cohort that comprised 66 IVF-conceived prepubertal children (IVF, n = 34; intracytoplasmic sperm injection, n = 32) and 69 matched naturally conceived controls. INTERVENTION(S): DNA methylation was...
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