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Comparative Genome and Network Centrality Analysis to Identify Drug Targets ofMycobacterium tuberculosis H37Rv

1 Jan 2015

Abstract excerpt

Potential drug targets of Mycobacterium tuberculosis H37Rv were identified through systematically integrated comparative genome and network centrality analysis. The comparative analysis of the complete genome of Mycobacterium tuberculosis H37Rv against Database of Essential Genes (DEG) yields a list of proteins which are essential for the growth and survival of the pathogen. Those proteins which are nonhomologous...

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PMID: 26618166
DOI: 10.1155/2015/212061

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