Article
Genetic polymorphisms in COL18A1 influence the development of osteosarcoma.
International journal of clinical and experimental pathology - 1 Jan 2015
Guo Zhihao, Zhang Tianji, Wu Juntao, Wang Hongwei, Liu Xiaotan, Tian Linqiang
Abstract excerpt
We conducted a case-control study to investigate the association of COL18A1 D104N polymorphism in the development of osteosarcoma in a Chinese population. Between May 2012 and May 2014, 141 patients with pathologically proven osteosarcoma and 341 were selected into this study. Genotyping of COL18A1 D104N was analyzed using polymerase chain reaction (PCR) coupled with restriction fragment length polymorphism...
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