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Article

Treatment Individualization in Colorectal Cancer

25 Aug 2015

Abstract excerpt

Colorectal cancer has been characterized as a genetically heterogeneous disease, with a large diversity in molecular pathogenesis resulting in differential responses to therapy. However, the currently available validated biomarkers KRAS, BRAF, and microsatellite instability do not sufficiently cover this extensive heterogeneity and are therefore not suitable to successfully guide personalized treatment. Recent...

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PMID: 26617477
DOI: 10.1007/s11888-015-0288-z

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