Identification of low abundance microbiome in clinical samples using whole genome sequencing

Abstract excerpt

Identifying the microbiome composition from primary tissues directly affords an opportunity to study the causative relationships between the host microbiome and disease. However, this is challenging due the low abundance of microbial DNA relative to the host. We present a systematic evaluation of microbiome profiling directly from endoscopic biopsies by whole genome sequencing. We compared our methods with other...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gastric Cancer Management and Outcomes
• Share to Helicobacter pylori-related gastroenterology studies
• Share to Mycobacterium research and diagnosis