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Clustering of immunological, metabolic and genetic features in latent autoimmune diabetes in adults: evidence from principal component analysis.

Internal and emergency medicine - 1 Jun 2016

Pes Giovanni Mario, Delitala Alessandro Palmerio, Errigo Alessandra, Delitala Giuseppe, Dore Maria Pina

Abstract excerpt

Latent autoimmune diabetes in adults (LADA) which accounts for more than 10 % of all cases of diabetes is characterized by onset after age 30, absence of ketoacidosis, insulin independence for at least 6 months, and presence of circulating islet-cell antibodies. Its marked heterogeneity in clinical features and immunological markers suggests the existence of multiple mechanisms underlying its pathogenesis. The...

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PMID: 26612761
DOI: 10.1007/s11739-015-1352-z

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TPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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