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Article

The effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.

Annals of the New York Academy of Sciences - 1 Jan 2016

Kruger Warren D, Gupta Sapna

Abstract excerpt

Cystathionine β synthase (CBS) is a key enzyme in the methionine and cysteine metabolic pathway, acting as a metabolic gatekeeper to regulate the flow of fixed sulfur from methionine to cysteine. Mutations in the CBS gene cause clinical CBS deficiency, a disease characterized by elevated plasma total homocysteine (tHcy) and methionine and decreased plasma cysteine. The treatment goal for CBS-deficient patients is...

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Identifiers

PMID: 26599618
DOI: 10.1111/nyas.12967
PMCID: PMC4801721

Genes

CBS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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