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Article

Genetic mutations strengthen functional association of LAP1 with DYT1 dystonia and muscular dystrophy.

Mutation research. Reviews in mutation research - 1 Jan 2000

Rebelo Sandra, da Cruz E Silva Edgar F, da Cruz E Silva Odete A B

Abstract excerpt

Lamina-associated polypeptide 1 (LAP1) is a ubiquitously expressed integral protein of the inner nuclear membrane. It interacts physically with lamins, torsinA, emerin and protein phosphatase 1; potentially providing a pivotal mechanism for transducing signals across the inner nuclear membrane. In neurons a functional protein complex is formed, comprising LAP1 and torsinA and in skeletal muscle LAP1 and emerin...

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Identifiers

PMID: 26596547
DOI: 10.1016/j.mrrev.2015.07.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic mutations strengthen functional association of LAP1 with DYT1 dystonia and muscular dystrophy.PMID 26596547Read ↗

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