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Article

Complete depletion of primordial germ cells in an All-female fish leads to Sex-biased gene expression alteration and sterile All-male occurrence.

BMC genomics - 18 Nov 2015

Liu Wei, Li Shi-Zhu, Li Zhi, Wang Yang, Li Xi-Yin, Zhong Jian-Xiang, Zhang Xiao-Juan, Zhang Jun, Zhou Li, Gui Jian-Fang

Abstract excerpt

BACKGROUND: Gynogenesis is one of unisexual reproduction modes in vertebrates, and produces all-female individuals with identical genetic background. In sexual reproduction vertebrates, the roles of primordial germ cells on sexual dimorphism and gonadal differentiation have been largely studied, and two distinct functional models have been proposed. However, the role of primordial germ cells remains unknown in...

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PMID: 26582363
DOI: 10.1186/s12864-015-2130-z
PMCID: PMC4652418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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