Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Production of Infectious Dengue Virus in Aedes aegypti Is Dependent on the Ubiquitin Proteasome Pathway

13 Nov 2015

Abstract excerpt

Dengue virus (DENV) relies on host factors to complete its life cycle in its mosquito host for subsequent transmission to humans. DENV first establishes infection in the midgut of Aedes aegypti and spreads to various mosquito organs for lifelong infection. Curiously, studies have shown that infectious DENV titers peak and decrease thereafter in the midgut despite relatively stable viral genome levels. However,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect symbiosis and bacterial influences
Share to Mosquito-borne diseases and control
Share to Studies on Chitinases and Chitosanases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26566123
DOI: 10.1371/journal.pntd.0004227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Production of Infectious Dengue Virus in Aedes aegypti Is Dependent on the Ubiquitin Proteasome PathwayPMID 26566123Read ↗

Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infectionSemantic proximity Read ↗

Transgene‐mediated suppression of the RNA interference pathway in A edes aegypti interferes with gene silencing and enhances S indbis virus and dengue virus type 2 replicationSemantic proximity Read ↗

Dengue virus replicates and accumulates in Aedes aegypti salivary glandsSemantic proximity Read ↗

Alterations in the Aedes aegypti Transcriptome during Infection with West Nile, Dengue and Yellow Fever VirusesSemantic proximity Read ↗

Cullin4 Is Pro-Viral during West Nile Virus Infection of Culex MosquitoesSemantic proximity Read ↗

Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegyptiSemantic proximity Read ↗

<i>Tudor-SN</i> promotes early replication of dengue virus in the <i>Aedes aegypti</i> midgutSemantic proximity Read ↗

Small RNA Profiling in Dengue Virus 2-Infected Aedes Mosquito Cells Reveals Viral piRNAs and Novel Host miRNAsSemantic proximity Read ↗

JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glandsSemantic proximity Read ↗

Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens MosquitoesSemantic proximity Read ↗

An evolutionarily conserved ubiquitin ligase drives infection and transmission of flavivirusesSemantic proximity Read ↗

Wolbachia mediates crosstalk between miRNA and Toll pathways to enhance resistance to dengue virus in Aedes aegyptiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.