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Suppression of the pelo protein by Wolbachia and its effect on dengue virus in Aedes aegypti

11 Apr 2018

Abstract excerpt

The endosymbiont Wolbachia is known to block replication of several important arboviruses, including dengue virus (DENV), in the mosquito vector Aedes aegypti.So far, the exact mechanism of this viral inhibition is not fully understood.A recent study in Drosophila melanogaster has demonstrated an interaction between the pelo gene and Drosophila C virus.In this study, we explored the possible involvement of the...

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PMID: 29641562
DOI: 10.1371/journal.pntd.0006405

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