Article
Suppression of fructose-bisphosphate aldolase C expression as a predictor of advanced oral squamous cell carcinoma.
Head & neck - 1 Apr 2016
Li Yue-Ju, Huang Tse-Hung, Hsiao Michael, Lin Been-Ren, Cheng Shih-Jung, Yang Cheng-Ning, Lai Wei-Ting, Wu Tai-Sheng, Fan Jia-Ruei, Kuo Mark Yen-Ping, Chang Cheng-Chi
Abstract excerpt
BACKGROUND: Glycolysis machinery regulates cancer cell behavior. However, the roles of these glycolysis enzymes in oral squamous cell carcinoma (OSCC) progression remain unknown. METHODS: Fructose-bisphosphate aldolase C (ALDOC) expression in OSCC patients and cell lines was detected using quantitative real-time polymerase chain reaction (PCR). The functions of ALDOC in migration and invasion were determined...
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