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Article

The genome-wide associated candidate gene ZNF804A and psychosis-proneness: Evidence of sex-modulated association.

PloS one - 1 Jan 2017

de Castro-Catala Marta, Mora-Solano Aurea, Kwapil Thomas R, Cristóbal-Narváez Paula, Sheinbaum Tamara, Racioppi Anna, Barrantes-Vidal Neus, Rosa Araceli

Abstract excerpt

BACKGROUND: The Zinc finger protein 804A (ZNF804A) is a promising candidate gene for schizophrenia and the broader psychosis phenotype that emerged from genome-wide association studies. It is related to neurodevelopment and associated to severe symptoms of schizophrenia and alterations in brain structure, as well as positive schizotypal personality traits in non-clinical samples. Moreover, a female-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28931092
DOI: 10.1371/journal.pone.0185072
PMCID: PMC5607189

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