Article
RNA-directed DNA methylation enforces boundaries between heterochromatin and euchromatin in the maize genome.
Proceedings of the National Academy of Sciences of the United States of America - 24 Nov 2015
Li Qing, Gent Jonathan I, Zynda Greg, Song Jawon, Makarevitch Irina, Hirsch Cory D, Hirsch Candice N, Dawe R Kelly, Madzima Thelma F, McGinnis Karen M, Lisch Damon, Schmitz Robert J, Vaughn Matthew W, Springer Nathan M
Abstract excerpt
The maize genome is relatively large (∼ 2.3 Gb) and has a complex organization of interspersed genes and transposable elements, which necessitates frequent boundaries between different types of chromatin. The examination of maize genes and conserved noncoding sequences revealed that many of these are flanked by regions of elevated asymmetric CHH (where H is A, C, or T) methylation (termed mCHH islands). These...
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