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Contrasting patterns of selection and drift between two categories of immune genes in prairie-chickens.

Molecular ecology - 1 Dec 2015

Bateson Zachary W, Whittingham Linda A, Johnson Jeff A, Dunn Peter O

Abstract excerpt

Immune-receptor genes of the adaptive immune system, such as the major histocompatibility complex (MHC), are involved in recognizing specific pathogens and are known to have high rates of adaptive evolution, presumably as a consequence of rapid co-evolution between hosts and pathogens. In contrast, many 'mediating' genes of the immune system do not interact directly with specific pathogens and are involved in...

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PMID: 26547898
DOI: 10.1111/mec.13459

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