Article
Genetic diversity in cytokines associated with immune variation and resistance to multiple pathogens in a natural rodent population.
PLoS genetics - 1 Oct 2011
Turner Andrew K, Begon Mike, Jackson Joseph A, Bradley Janette E, Paterson Steve
Abstract excerpt
Pathogens are believed to drive genetic diversity at host loci involved in immunity to infectious disease. To date, studies exploring the genetic basis of pathogen resistance in the wild have focussed almost exclusively on genes of the Major Histocompatibility Complex (MHC); the role of genetic variation elsewhere in the genome as a basis for variation in pathogen resistance has rarely been explored in natural...
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