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Article

Quantitative disease resistance: to better understand parasite-mediated selection on major histocompatibility complex.

Proceedings. Biological sciences - 7 Feb 2012

Westerdahl Helena, Asghar Muhammad, Hasselquist Dennis, Bensch Staffan

Abstract excerpt

We outline a descriptive framework of how candidate alleles of the immune system associate with infectious diseases in natural populations of animals. Three kinds of alleles can be separated when both prevalence of infection and infection intensity are measured--qualitative disease resistance, quantitative disease resistance and susceptibility alleles. Our descriptive framework demonstrates why alleles for...

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Identifiers

PMID: 21733902
DOI: 10.1098/rspb.2011.0917
PMCID: PMC3234550

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