Article
Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases.
Journal of molecular and cellular cardiology - 1 Dec 2015
Calore Martina, De Windt Leon J, Rampazzo Alessandra
Abstract excerpt
After the recent description of the human genome by the ENCODE and the FANTOM consortia, major attention has been addressed to the so-called "genomic noise", which mainly consists of noncoding RNAs (ncRNAs). Among them, microRNAs and long non-coding RNAs have been demonstrated to modulate gene expression and to be involved in several human diseases. Since ncRNAs and their targets are encoded in the genome,...
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