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Methylated B3GAT2 and ZNF793 Are Potential Detection Biomarkers for Barrett's Esophagus

6 Nov 2015

Abstract excerpt

BACKGROUND: Barrett's esophagus (BE) is a preneoplastic condition in which normal esophageal squamous epithelium (SQ) is replaced by specialized intestinal metaplasia. It is the presumed precursor for esophageal adenocarcinoma (EAC) as well as the strongest risk factor for this cancer. Unfortunately, many patients with BE go undiagnosed under the current BE screening guidelines. The development of noninvasive and...

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PMID: 26545406
DOI: 10.1158/1055-9965.epi-15-0370

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