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Molecular diagnostics: techniques and recommendations for 1p/19q assessment

31 Oct 2015

Abstract excerpt

Several morphology- and polymerase chain reaction (PCR)-based methods for chromosome 1p 19q deletion status assessment are available. Important prerequisites for all molecular techniques concern tissue quality and selection of regions of interest. The most common methods for diagnostic 1p 19q assessment are fluorescence in situ hybridization and PCR-based microsatellite analysis. While the latter requires the use...

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PMID: 26545171
DOI: 10.2217/cns.15.28

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