Article
[Safety Evaluation of Rare Sugar Syrup: Single-dose Oral Toxicity in Rats, Reverse Mutation Assay, Chromosome Aberration Assay, and Acute Non-Effect Level for Diarrhea of a Single Dose in Humans].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - 1 Jan 2015
Yamada Takako, Iida Tetsuo, Takamine Satoshi, Hayashi Noriko, Okuma Kazuhiro
Abstract excerpt
The safety of rare sugar syrup obtained from high-fructose corn syrup under slightly alkaline conditions was studied. Mutagenicity of rare sugar syrup was assessed by a reverse mutation assay using Salmonella typhimurium and Escherichia coli, and an in vitro chromosomal aberration assay using Chinese hamster lung cell line (CHL/IU). No mutagenicity of rare sugar syrup was detected under these experimental...
Topics
- Administration, Oral
- Animals
- Cells, Cultured
- Chromosome Aberrations
- Cricetinae
- Cricetulus
- Diarrhea
- Dose-Response Relationship, Drug
- Escherichia coli
- Female
- Food Safety
- High Fructose Corn Syrup
- Humans