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Article

NUP160–SLC43A3 Is a Novel Recurrent Fusion Oncogene in Angiosarcoma

1 Nov 2015

Abstract excerpt

Angiosarcoma is a malignant vascular tumor originating from endothelial cells of blood vessels or lymphatic vessels. The specific driver mutations in angiosarcoma remain unknown. In this study, we investigated this issue by transcriptome sequencing of patient-derived angiosarcoma cells (ISO-HAS), identifying a novel fusion gene NUP160-SLC43A3 found to be expressed in 9 of 25 human angiosarcoma specimens that were...

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PMID: 26527604
DOI: 10.1158/0008-5472.can-15-0418

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