Article
[Naturally occurring NS5B variants resistant to non-nucleoside or nucleoside polymerase inhibitors among treatment-naïve hepatitis C patients in south China].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Sept 2015
Li Zhanyi, Liu Ying, Cai Qingxian, Shao Xiaoqiong, Yan Ying, Zhao Zhixin
Abstract excerpt
OBJECTIVE: To determine the prevalence of mutations in the non-structural protein 5B (NS5B) of the hepatitis C virus (HCV),which are associated with natural resistance to non-nucleoside and nucleoside polymerase inhibitors (PIs),in treatment-naive hepatitis C patients in south China. METHODS: A nested PCR protocol that amplified three different regions of NS5B was used to detect the naturally occurring...
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