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Article

New Genetic Forms of Childhood-Onset Primary Osteoporosis.

Hormone research in paediatrics - 1 Jan 2015

Kämpe Anders J, Mäkitie Riikka E, Mäkitie Outi

Abstract excerpt

Recent developments in genetic technology have given us the opportunity to look at diseases in a new and more detailed way. This Mini Review discusses monogenetic forms of childhood-onset primary osteoporosis, with the main focus on osteoporosis caused by mutations in WNT1 and PLS3, two of the most recently discovered genes underlying early-onset osteoporosis. The importance of WNT1 in the accrual and maintenance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26517534
DOI: 10.1159/000439566

Genes

PLS3
WNT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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New Genetic Forms of Childhood-Onset Primary Osteoporosis.PMID 26517534Read ↗

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Early-Onset Osteoporosis.Semantic proximity Read ↗

PLS3 Mutations in X-Linked Osteoporosis: Clinical and Genetic Features in Five New Families.Semantic proximity Read ↗

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Identification of a novel splicing mutation and genotype-phenotype correlations in rare PLS3-related childhood-onset osteoporosis.Semantic proximity Read ↗

Osteoporosis: A Silent Disease with Complex Genetic Contribution.Semantic proximity Read ↗

Identification of a novel splicing mutation and genotype-phenotype correlations in rare PLS3-related osteoporosisSemantic proximity Read ↗

Osteoporosis Caused by Monoallelic Variant of WNT1 Gene in Four Pediatric Patients.Semantic proximity Read ↗

Osteoporosis related to WNT1 variants: a not infrequent cause of osteoporosis.Semantic proximity Read ↗

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