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Influence of a subinhibitory concentration of vancomycin on the in vitro expression of virulence-related genes in the vancomycin-resistant Enterococcus faecalis.

Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000

Moura Tiane Martin de, Campos Fabrício Souza, Caierão Juliana, Franco Ana Claudia, Roehe Paulo Michel, d'Azevedo Pedro Alves, Frazzon Jeverson, Frazzon Ana Paula Guedes

Abstract excerpt

INTRODUCTION: Exposure to subinhibitory concentrations (SICs) of antimicrobials may alter the bacterial transcriptome. METHODS: Here, we evaluated the expression of nine virulence-related genes in vancomycin-resistant enterococci (VRE) urinary tract infection isolates grown at SICs of vancomycin. RESULTS: A Subinhibitory concentrations of vancomycin interferes with gene modulation, but does not affect the...

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PMID: 26516976
DOI: 10.1590/0037-8682-0017-2015

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