Article
NDRG4 stratifies the prognostic value of body mass index in colorectal cancer.
Oncotarget - 12 Jan 2016
Zheng Jianyong, Li Yunming, Zhu Shaojun, Li Jipeng, Zhao Qingchuan, Ji Gang, Wang Weizhong, Chu Dake
Abstract excerpt
NDRG4 is a novel candidate tumor suppressor and can inhibit PI3K/AKT signal which is related with energy balance and related carcinogenesis. In the present study, we investigated whether NDRG4 status could modify the association of obesity with clinical outcome of colorectal cancer. For this purpose, a hospital-based prospective study cohort of 226 colorectal cancer patients was involved. NDRG4 mRNA levels were...
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