Article
Comparison of three quantitative HCV RNA assays in samples from HCV genotype 1- or 4-infected patients treated with the NS3/4A protease inhibitor simeprevir.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2015
Fevery Bart, Susser Simone, Lenz Oliver, Cloherty Gavin, Perner Dany, Gilles Leen, De Locht Patrick, Picchio Gaston, De Meyer Sandra, Sarrazin Christoph
Abstract excerpt
BACKGROUND: Monitoring HCV RNA levels during treatment is an important tool for managing protease-inhibitor-based regimens, and different assays used in clinical practice can impact treatment decisions. OBJECTIVES: The concordance of three HCV RNA assays was determined, and their impact on treatment decisions assessed using samples from HCV genotype (GT) 1- and GT4-infected patients treated with the NS3/4A...
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