Article
Identification of genetic polymorphisms that predict responder/non-responder profiles to the RhD antigen.
Molecular immunology - 1 Dec 2015
Tan Joanne C G, Armstrong Nicola J, Yuan Fang Fang, Flower Robert L, Dyer Wayne B
Abstract excerpt
BACKGROUND: Regular plasma donors who produce high titre anti-D immunoglobulin (Ig) are overseen by the Australian Red Cross Blood Service RhD Program. New donors to the program are immunised with small amounts of RhD-positive RBCs, whilst donors who have developed anti-D due to previous RhD-incompatible blood transfusion or pregnancy are boosted with RhD-positive RBCs to maintain a high level of serum anti-D Ig....
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