Article
Influence of ERCC2 gene polymorphisms on the treatment outcome of osteosarcoma.
Genetics and molecular research : GMR - 21 Oct 2015
Liu Z F, Asila A L J, Aikenmu K, Zhao J, Meng Q C, Fang R
Abstract excerpt
We conducted a prospective study to investigate the role of ERCC2 gene polymorphisms on the outcome of cisplatin-based treatment in patients with osteosarcoma. A total of 115 patients with osteosarcoma were included in our study. Genotyping of ERCC2 Asn312Asp (rs1799793) and Lys751Gln (rs13181) was performed using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry method. Of the 115...
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