Article
Effect of retS gene on antibiotics production in Pseudomonas fluorescens FD6.
Microbiological research - 1 Nov 2015
Zhang Qingxia, Xiao Qi, Xu Jingyou, Tong Yunhui, Wen Jia, Chen Xijun, Wei Lihui
Abstract excerpt
A hybrid sensor kinase termed RetS (regulator of exopolysaccharide and Type III secretion) controls expression of numerous genes in Pseudomonas aeruginosa. To investigate the function of RetS in P. fluorescens FD6, the retS gene was disrupted. Genetic inactivation of retS resulted in enhanced production of 2, 4-diacetylphloroglucinol, pyrrolnitrin, and pyoluteorin. The retS mutant also exhibited significant...
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